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Sometimes, if you think a tablet might cause a nightmare, it can increase the risk of having one. For some types of statin, it’s better to take them at night, because that’s when they have a bigger effect on reducing cholesterol. However, the most important thing is that you take them regularly, rather than not at all. Are there any food or drinks I should avoid? It’s a useless biomarker in terms of predicting someone’s risk of heart disease and therefore we shouldn’t obsess about lowering it," he says. Instead, he believes the best predictor of the risk of heart disease is reached by measuring the ratio of total cholesterol to HDL, or 'good' cholesterol. They work by inhibiting an enzyme in the liver called HMG-CoA reductase. This reduces the production of cholesterol in the liver and so reduces cholesterol levels in the blood.
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Like all medications, statins have potential side effects. The most common are muscular aches and pains, but many people experience no side effects. About one in 250 people in the UK have familial hypercholesterolaemia (FH), an inherited condition that causes high levels of cholesterol and which can also be treated with statins. If you’re pregnant, breastfeeding or planning a pregnancy, you shouldn't take statins. If you’re already taking statins and recently found out you’re pregnant or would like to become pregnant, speak to your GP. What are the side effects of statins? In it, he examines the claims for statins – including whether lowering cholesterol really is the key to preventing heart disease.Exercise is important. "Exercise itself reduces insulin resistance. It keeps your cells more sensitive to insulin and therefore means there’s less insulin required to maintain your blood glucose in normal range, and therefore less damage to the cells of the inner lining of the heart arteries." Weigh up the pros and cons of taking a statin and remember, a healthy diet, physical activity and not smoking are also important for your heart health. In the world’s ‘blue zones’ – areas of notable longevity and almost no heart disease – "They weren’t pounding in the gym, running marathons. They were just moving all the time, not being sedentary." Nor he adds, were they taking statins. So what is the evidence for their benefits? Dr Aseem Malhotra, author of the bestselling The 21-Day Immunity Plan and co-author of the bestselling The Pioppi Diet , examines the claims for statins and their role in lowering cholesterol and preventing heart disease. He introduces us to his targeted heart-health plan, which, with a diet plan, recipes and advice on reducing stress and increasing movement, can help us to live statin-free and take control of our own health. If your doctor says you need it, a statin is the best way of lowering your cholesterol. Living a healthy life, whether you're taking a statin or not, is another way of lowering your cholesterol. You can do this by:
Pioppi Diet: The 21-Day Anti-Diabetes Lifestyle Plan as The Pioppi Diet: The 21-Day Anti-Diabetes Lifestyle Plan as
The foods we should eat? "A combination of oily fish, nuts, whole fruit and vegetables, extra virgin olive oil - and whatever else as long as you’re minimising the sugar and low quality carbohydrate, the breads and the pastas." The main differences are in how much they lower cholesterol. They can be split into two groups – low-intensity statins (for example, pravastatin and simvastatin) and high-intensity statins (such as atorvastatin and rosuvastatin). For most people, a lower-intensity statin will be enough to reduce their cholesterol sufficiently, but if it’s not, your doctor may want to increase the dose or switch to a higher-intensity one. What side effects are there? Note: optimal metabolic health (including Low levels of insulin and a normal waste circumference achieved through diet and lifestyle) means the risk of developing heart disease is markedly reducedMuscular aches and pains are the most common. It’s natural to associate symptoms with a new tablet but we all get muscle aches from time to time, so it’s difficult to know if they are due to medication or just to do with everyday life. Most people experience no side effects from statins. For some, though, they are an issue. If this is the case, ask your doctor about trying a different statin. He is a frequent expert commentator in print and broadcast media in the UK and internationally, having written for a wide range of publications such as the BMJ, British Journal of Sports Medicine, and European Scientist, and has had feature articles written about him in papers such as The New York Times, the Guardian and the Daily Telegraph. We've followed an eight-step process to make sure this content is reliable, accurate and trustworthy. Learn how we make our health information reliable and easy to understand.
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